Co Q10 And
Heart Muscle Damage

CoQ10 and Prevention of Myocardial Damage

Sifting through the medical journals for information on Co Q10 and heart disease can be difficult work. But sometimes it is worth the effort. Once you parse through the vocabulary you can discover some wonderful heart health jewels. 

Studies involving the benefits of CoQ10 supplementation can be found sprinkled throughout the technical jargon of the medical community. On this page we will look at a few studies surrounding one very important heart health issue involving CoQ10:

Myocardial Damage.

By the way, if you don’t really know what CoQ10 is it will be helpful for you to return to the Main CoQ10 Page and follow the discussion. 

One does not have to read through the reports of scientific studies very long before confronting a number of intimidating words. Words such as…

  • Cardiomyopathy
  • Myocardial infarction
  • Ischemia
  • Reperfusion

Such specialty words are necessary in many professions. They make language more expedient, at least for those on the inside. But if we take a moment to do a little layman’s translating we too can benefit from some of the important issues hidden within the medical journals.

  • The word myocardial refers simply to heart muscle mass.
  • An infarct is an area of tissue death due to a lack of oxygen.
  • Therefore a myocardial infarction is irreversible injury (tissue death) involving the heart muscle tissue. This term is used as a synonym for a heart attack.
  • Ischemia is a low oxygen state. It is usually caused by some obstruction to the flow of blood through the arteries. Obviously, then, ischemia can lead to an infarct.
  • Reperfusion is the restoration of blood flow to an organ or tissue. After a heart attack, an immediate goal is to quickly open blocked arteries and reperfuse the heart muscles. Early reperfusion minimizes the extent of heart muscle damage and preserves the pumping function of the heart.
  • Cardiomyopathy refers to disease affecting the heart muscles. Often such diseases/conditions are of an obscure nature.

This quick vocabulary lesson will not make reading medical journals as easy (or enjoyable) as reading a mystery novel. But it will help us through our discussion of Co Q10 and heart health.

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Are there health issues – in addition to your heart health – that concern you? Like…

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  • Your body holding on to too many toxins?
  • And chronic inflammation?
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  • And poor nutrition?
  •  And foods that stress your system?

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CoQ10 and Heart Attack Damage

It is not news to any of us that a heart attack is something to be avoided at all costs. Nor is it news that the damage caused by a heart attack can result in problems for the rest of one’s life. Therefore any treatment that can help prevent a heart attack or improve recovery from a heart attack is well worth our attention.

If that treatment has been well studied and involves a completely natural substance then it should peak our interest at the very least.

The fact is Co Q10 and heart disease has been the subject of many studies. This is particularly true in relation to heart attack and the restoration of heart function after a heart attack. What follows are the results of those studies. 

Animal studies have shown that the damage caused by starving the heart of oxygen and then restoring oxygen flow (ischemia-reperfusion) can be decreased by pretreating the animals with CoQ10. 

This process becomes real to us during surgery when clamping of the arteries causes the heart to be starved of oxygen. Even after the oxygen flow is restored the heart may be damaged. In such instances it has been found that… 

Three out of 4 placebo-controlled trials found that coenzyme Q10 pretreatment (60-300 mg/d 7-14 days prior to surgery) provided some benefit in short-term outcome measures after CABG surgery.

To read a great article from which this quote was taken click here.

Studies Concerning CoQ10 Therapy for Cardiomyopathy

Again, we are here concerned with diseases or conditions that affect the heart muscles’ ability to function. Following we will discuss three clinical studies demonstrating the effectiveness of CoQ10 therapy in such cases. 

The first study involved 143 cases of chronic cardiomyopathy where there was no indication of heart muscle enlargement. Each patient was receiving traditional medical treatments. In addition to these treatments each patient received 100 mg of CoQ10 by oral supplementation per day. At the time the article was written the study had been going on for 6 years. 

The researchers recorded blood levels of Co Q10 and heart muscle function. As expected blood levels of CoQ10 increased leveling off at about three months. 

Heart muscle function also showed significant improvement. The average ejection fraction at the beginning of the CoQ10 study was 44%.

Ejection fraction is a measurement indicating how well the ventricles (heart muscle chambers) can pump blood.

Within six months the average ejection fraction rose to 60%. The average continued to climb until it leveled out at 84%. 

The study reported the patients as showing statistically significant improvement. Eighty-five percent of the patients improved by one or two classification levels. To read an abstract of this study please use the link below: 

A six-year clinical study of therapy of cardiomyopathy with coenzyme Q10. 

Another study on Co Q10 and heart therapy involved 115 patients suffering from some level of cardiomyopathy. 88 patients of the original 115 completed the trial. 

Like the previous study measurements of ejection fraction were used as one of the main indicators for heart function improvement. 

Between 75% and 85% of the 88 patients showed significant improvement with the CoQ10 therapy.

Patients with the lowest ejection fractions (weakest hearts) showed the greatest improvement in heart performance.

These patients began the study with ejection fractions between 10% and 30%. The improvements were calculated to be between 115% and 210%. 

Patients with the highest ejection fractions (strongest hearts) at the beginning of the study showed lesser improvement. These began the study with ejection fractions between 50% and 80%. The average improvements were between 15% and 25%. 

These heart patients were also classified functionally. The lower the class the stronger the heart function. 

Twenty-one patients were initially classified as class IV, the worst category. Of these 17 were placed in a lower (better) class after receiving CoQ10 therapy.

Sixty-two of the patients were originally placed in class III. All but ten of these moved to a lower class after receiving the Co10 therapy. Four out of five of the class II patients moved to class I. 

Nearly half of all patients were CoQ10 deficient at the beginning of the study. To read the abstract on this study please use the link below: 

Effective and safe therapy with coenzyme Q10 for cardiomyopathy.

The third study on Co Q10 and heart therapy we will consider is much like the two above except that it was primarily concerned with survival rates for patients suffering from cardiomyopathy. 

Out of a total 137 cardiomyopathy patients, 43 had ejection fractions below 40% (average 25.1%). The average blood CoQ10 level for these patients was 0.85 micrograms/ml. After CoQ10 treatment this level rose to between 1.7 and 2.3 micrograms/ml. 

After treating these patients for approximately 3 months with CoQ10 the average ejection fractions rose to 41.6%. Ejection fraction continued to rise at a lesser rate as treatment continued. 

Survival rates also rose dramatically. To quote the abstract…

The survival rates for all 137 patients treated with CoQ10 and for the 43 patients with EF below 40% were both about 75%/46 months. These two survival rates were comparable between 24 and 46 months, which is of extraordinary significance and importance when compared to survival of about 25%/36 months for 182 patients with EF below 46% on conventional therapy without CoQ10.

Please see the abstract on this study by using the link below. 

Pronounced increase of survival of patients with cardiomyopathy when treated with coenzyme Q10 and conventional therapy. 

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